鱼尼丁受体抑制剂及其作用机制研究进展

近年来,以鱼尼丁受体(ryanodine receptor,Ry R)为靶标的杀虫剂研发取得了突破性进展。介绍了Ry R结构和功能,以及Ry R为靶标的杀虫剂的创制历程,作用机制的研究进展。该类杀虫剂靶标新颖,作用机理独特、高效,对非靶标生物安全(如哺乳动物等)以及与传统农药无交互抗性,具有很好的发展前景。     

基于ANSYS Workbench的大型挤压造粒机双螺杆芯轴有限元分析

大型挤压造粒机芯轴是非常重要的零件,为避免其失效破坏,本文分别采用有限元分析与传统理论力学计算对其强度进行验算。     

Experimental and quantum chemical studies of the effect of poly ethylene glycol as corrosion inhibitors of aluminum surface

The corrosion inhibition of poly ethylene glycol (PEG) toward the aluminum surface in 1.0 M HCl has been studied by weight loss and polarization techniques. The results showed that the PEG acts as a good inhibitor and the inhibition efficiency is due to the anodic and cathodic inhibition (mixed type). The thermodynamic functions were calculated to find a good correlation with the inhibition efficiency. Quantum chemical parameters were calculated using ab initio and DFT methods to find a good correlation with the inhibition efficiency. A good correlation was found between the theoretical calculations and experimental observations.     

Recent Advances in Food-Packing,Pharmaceutical and Biomedical Applications of Zein and Zein-Based Materials

Zein is a biodegradable and biocompatible material extracted from renewable resources; it comprises almost 80% of the whole protein content in corn. This review highlights and describes some zein and zein-based materials, focusing on biomedical applications. It was demonstrated in this review that the biodegradation and biocompatibility of zein are key parameters for its uses in the food-packing, biomedical and pharmaceutical fields. Furthermore, it was pointed out that the presence of hydrophilic-hydrophobic groups in zein chains is a very important aspect for obtaining material with different hydrophobicities by mixing with other moieties (polymeric or not), but also for obtaining derivatives with different properties. The physical and chemical characteristics and special structure (at the molecular, nano and micro scales) make zein molecules inherently superior to many other polymers from natural sources and synthetic ones. The film-forming property of zein and zein-based materials is important for several applications. The good electrospinnability of zein is important for producing zein and zein-based nanofibers for applications in tissue engineering and drug delivery. The use of zein’s hydrolysate peptides for reducing blood pressure is another important issue related to the application of derivatives of zein in the biomedical field. It is pointed out that the biodegradability and biocompatibility of zein and other inherent properties associated with zein’s structure allow a myriad of applications of such materials with great potential in the near future.     

弯管顺序输送影响因素研究

相邻批次的油品在进行成品油顺序输送时会产生一定量的混油。通过CFD软件,针对弯管顺序输送的条件下通过改变流速、粘度和弯径比来进行研究比较。结果表明,流速越小混油油头越尖锐,并且流速越大混油油头越靠近管道弯曲处;而后行油品粘度较大的比粘度较小的混油油头的位置相对滞后;弯径比较大的管道混油流经下游管段时混油段长度越长。其结果与工程现象基本吻合。为实际生产提供了一定的理论参考。     

径向基函数神经网络在砂体厚度预测中的应用

目前,人工智能神经网络在地震储层参数的预测方面具有广泛的应用,最常用的为BP神经网络,但是效果并不是十分理想。径向基函数神经网络(RBFN)是一种前馈神经网络,其在函数逼近、模式识别方面都优于BP网络,已经在岩性识别、孔渗预测方面取得了较好的应用效果。本文首次将此方法运用于预测砂体厚度,利用地震属性信息和神经网络的学习,基于实际数据计算,最后计算出相应的砂体厚度值,并与实测值进行误差分析。实例分析表明,利用径向基函数神经网络进行砂体厚度预测具有一定的可行性和实用价值。     

硫醇在金属表面自组装成膜的研究进展

金属表面自组装分子膜的研究近年来受到广泛关注,对金属表面自组装单分子膜的研究具有广泛的使用价值与应用价值。本以Au、Ag、Cu、Fe为代表,介绍了硫醇在其表面硫醇自组装成膜的过程、表面膜的结构、表面膜的特点和成膜的机理的研究进展,并且对其发展前景作了展望。     

2000m~3大型钢制球罐上极板开孔结构的应力强度评定

应用有限元软件对钢制球罐的上极板进行了两种工况下的分析,考虑到上极板的结构特性和承载特性,结构采用ANSYS 12.1有限元软件中提供的20节点单元(solid 95)进行建模,施加位移约束和载荷边界条件之后,得到了球罐上极板开孔结构的应力及应变云图,并依据JB 4732-1995《钢制压力容器分析设计标准》,参照GB12337—1998《钢制球形储罐》对其进行了强度评定。计算结果表明,该球罐的上极板结构是可靠的,为后续大型球罐的设计和优化提供了工程实用价值。     

油气田高氯废水COD测定的两种方法比较研究

油气田废水成分复杂,含盐量高,利用传统方法测定COD结果偏差大。利用系统的正交实验对比研究了氯气校正法与重铬酸盐法测定油气田高含盐废水COD的适用性,研究结果表明,重铬酸钾法测定误差大,氯气校正法能准确可靠地测定油气田废水的COD值,其测定结果 COD100时,误差在30%以内,COD100时,误差在10%以内,回收率在102%~119%,并且重现性良好,能够满足分析测试的要求。